Metabolic syndrome after Menopause and the role of hormone replacement

Metabolic syndrome after Menopause and the role of hormone replacement

Metabolic Syndrome is defined as having three or more of the following conditions:

  • Abdominal Obesity
  • Triglyceride levels over 150
  • HDL cholesterol levels less than 40
  • Consistent blood pressure readings over 130/85
  • Fasting blood glucose over 100

MBS may occur in 40% of post menopausal women and is largely determined by overweight status and obesity. Weight gain increases prior to menopause and hormone therapy generally decreases abdominal fat.  Women who have MBS have elevations in several inflammation and clotting factors. Hormone therapy reduces some inflammation factors and also has shown to be helpful with lipids (cholesterol). The addition of hormone replacement with diet and exercise can help women lose weight and can reduce the risks of having MBS.

2008 May 20;60(1):10-8. doi: 10.1016/j.maturitas.2008.02.008. Epub 2008 Apr 14.

https://www.ncbi.nlm.nih.gov/pubmed/18407440